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Total superoxide dismutase activity is lower in all colorectal carcinoma groups than in control, and there is a significant increase in tumor stage IV when compared with tumor stage II

J Nutr 122 : 420427 Stipanuk MH, Dominy JE Jr, Lee JI, Coloso RM 2006 Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism

This occurs because the pituitary gland and adipose tissue are stimulated to produce androgens and luteinizing hormone, respectively, in response to increasing levels of androgens, which in turn heighten insulin resistance (IR) and hyperinsulinemia (Hg)

These results from a small pilot study cannot support a clinical recommendation

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